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Small Vendors

These databases have been provided to us under collaborative agreements with each respective vendor. Molecules in the original catalogs may not appear in ZINC because they do not pass our filters, or they have not been processed yet. ZINC may be used free of charge for research by individuals and institutions. Whereas you are free to share the results of a ZINC search or a screen of molecules from ZINC, you may not redistribute major portions of ZINC without the express written permission of John Irwin. Additional usage notes may be found below the table.
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Vendor
Information

Name
Email
Phone
Fax

Catalog
Information

Source- entries,
Version/ Date

ZINC
Information

Loaded,
Filtered,
Sole- source,
Depleted

Diversity
Information

Cluster represent-
atives
at a given Tanimoto cutoff

MedChem Express
sales at medchemexpress.com 
p.+1 609 228 6898
f.+1 609 228 5909
5115
2015-12-04
4662 download
11
660
NYA
90%:3438
80%:2998
70%:2594
60%:2026
AnalytiCon Discovery NP
sales at ac-discovery.com 
p.+49 331 2300-335
f.+49 331 2300-333
5154
2013-02-17
11247 download
684
4549
NYA
90%:2352
80%:1440
70%:792
60%:402
Maybridge Building Blocks
Maybridge.Sales at thermofisher.com 
p.+44 1840 772046
f.+44 1840 772208
5359
2015-04-16
5487 download
0
40
NYA
90%:4090
80%:2665
70%:1506
60%:758
Tyger Building Blocks
sales at tygersci.com 
p.(888) 329-8990
f.(609) 434-0143
5745
2012-05-14
6324 download
381
436
NYA
90%:3870
80%:2601
70%:1487
60%:717
Chemical Block BB
order at chemical-block.com 
p.+7 095 1356343
f.+7 095 1372966
5761
2013-02-16
6886 download
105
24
NYA
90%:4623
80%:3214
70%:1999
60%:1064
BioBlocks BB
sales at bioblocks.com 
p.+1 858 558 5900
f.+1 858 558 5911
5840
2014-05-09
6753 download
106
25
NYA
90%:4629
80%:3207
70%:2003
60%:1057
Tocris
info at tocris.co.uk 
p.+44 117 916 3333
f.+44 117 916 3344
5911
2014-10-03
3644 download
462
533
NYA
90%:2779
80%:2484
70%:2163
60%:1695
Synchem UG and Co KG
info at synchem.de 
p.+49 5662 40873 0
f.+49 5662 40873 20
6036
2014-09-08
5950 download
315
583
NYA
90%:4000
80%:2560
70%:1506
60%:874
StruChem BB
service at struchem.com 
p.+86 512 63009836 ext 109
f.+86 512 63006936
6271
2014-04-29
6419 download
452
75
NYA
90%:3945
80%:2346
70%:1177
60%:654
Asinex Building Blocks
busdev at asinex.com 
p.+7 495 780 3417
f.+7 095 780 3419
6622
2012-08-01
9065 download
58
6
NYA
90%:4580
80%:2803
70%:1472
60%:747
Novochemy Building Blocks
info at novochemy.com 
p.phone
f.fax
6892
2012-06-19
6751 download
28
175
NYA
90%:4846
80%:2432
70%:1084
60%:491
Boerchem Pharmatech BB
info at boerchemical.com 
p.+86 571 86071772
f.+86 571 86071772
7488
2014-06-11
7482 download
457
65
NYA
90%:5106
80%:3209
70%:1800
60%:953
Synergy Scientific BB
sales at synergy-scientific.com 
p.+86 21 51816459-8010
f.+86-21-51816740
7720
2013-02-01
7625 download
140
36
NYA
90%:5108
80%:2625
70%:1241
60%:627
EDASA Scientific
info at EDASAscientific.com 
p.+7 (903) 127-47-96
f.fax
8354
2015-04-15
9772 download
90
1769
NYA
90%:5072
80%:2810
70%:1474
60%:697
EvoBlocks
info at evoblocks.com 
p.+36-20-575-7305
f.none
8367
2012-02-23
10455 download
198
788
NYA
90%:1661
80%:575
70%:315
60%:161
Specs Building Blocks
info at specs.net 
p.+31 88 5255111
f.+31 88 5255151
8930
2015-11-23
8812 download
113
158
NYA
90%:6203
80%:4131
70%:2451
60%:1299
J&K Chemical
info at jk-scientific.com 
p.+852 2810 5022 x 875
f.+852 2810 5033 x 405
9921
2013-04-04
8679 download
997
370
NYA
90%:5152
80%:2802
70%:1283
60%:629
Zelinsky Institute Building Blocks
sales at zelinsky.com 
p.+1 302 250 4980
f.+1 302 292 8520
10732
2012-06-19
11783 download
117
410
NYA
90%:5361
80%:2126
70%:1114
60%:557
Rare Chemicals
info at rarechem.de 
p.+49 431 5606 600
f.+49-431-5606-608
10830
2012-08-06
5578 download
344
2291
NYA
90%:2645
80%:1694
70%:1032
60%:544
IBScreen BuildingBlocks
screen at ibscreen.chg.ru 
p.+7 (095) 788 0651
f. +7 (095) 788 0652
11650
2013-02-25
13532 download
358
53
NYA
90%:7884
80%:4530
70%:2346
60%:1077
Indofine
chemical at indofinechemical.com 
p.+1 908 359 6778
f.+1 908 359 1179
12030
2012-10-25
10240 download
1565
1471
NYA
90%:3909
80%:2097
70%:1081
60%:560
Lab Seeker Building Blocks
sales at labseeker.com 
p.+86 512 63008651
f.+86 512 63006936
14096
2014-05-13
14522 download
781
0
NYA
90%:8766
80%:4664
70%:2121
60%:1047
Maybridge Hit Finder
info at maybridge.com 
p.no phone
f.no fax
14400
2012-05-08
18663 download
224
1140
NYA
90%:14295
80%:14227
70%:12989
60%:5710
Peakdale
sales at peakdale.com 
p.+1 302 838 0420
f.+1 302 838 0421
15339
2011-12-06
17066 download
330
15117
NYA
90%:7833
80%:2672
70%:991
60%:418
Frontier Scientific Services
customerservice at frontierssi.com 
p.+1 888-577-2734
f.+1 302-266-8296
65119
2012-01-18
14752 download
2173
544
NYA
90%:8800
80%:4799
70%:2198
60%:939
MolMall (formerly Molecular Diversity Preservation International)
samples at molmall.net 
p.+41 21 802 18 34
f.no fax
15723
2014-09-08
30245 download
61
2103
NYA
90%:12681
80%:7611
70%:4330
60%:2287
Life Chemicals Building Blocks
George.Bondar at lifechemicals.com 
p.+1 905 634 5212
f.+1 905 634 4719
15968
2015-12-03
14312 download
245
2017
NYA
90%:7554
80%:4462
70%:2417
60%:1108
Key Organics Building Blocks
enquiries at keyorganics.ltd.uk 
p.+44 1840 212137
f.+44 1840 213712
16712
2015-07-24
17299 download
280
279
NYA
90%:11969
80%:7158
70%:3373
60%:1419
Vesino Industrial Co Ltd
info at vsnchem.com 
p.0086 22 27466330
f.0086 22 27455635
16957
2014-10-10
17794 download
968
320
NYA
90%:10602
80%:5838
70%:2616
60%:1241
APIChem
sales at apichemistry.com 
p.+86 138 5819 1376
f.+86 571 5605 9907
17404
2012-05-04
17865 download
841
126
NYA
90%:9909
80%:5339
70%:2640
60%:1356
Bosche Scientific
sales at boschesci.com 
p.+1 732 565 9988
f.+1 732 875 0899
17544
2013-02-21
18734 download
868
1099
NYA
90%:10600
80%:5781
70%:2830
60%:1369
Acros Organics
info at acros.com 
p.N/A
f.+32 14 59 34 34
17674
2015-01-03
14043 download
1156
90
NYA
90%:8432
80%:4274
70%:1827
60%:857
ChemBridge BuildingBlocks
support at chembridge.com 
p.858 451 7400
f.858 451 7401
18404
2015-11-23
17998 download
254
135
NYA
90%:9356
80%:4771
70%:2114
60%:859
Element Store BB
service at b2star.com 
p.+86 0512-81665512
f.no fax
19335
2015-06-21
20257 download
2894
1078
NYA
90%:10156
80%:6216
70%:3221
60%:1627
TCI
sales at tci-uk.co.uk 
p.+44 1865 78 45 60
f.+44 1865 78 45 61
20310
2012-03-01
17320 download
2570
1110
NYA
90%:8369
80%:3998
70%:1722
60%:817
AsisChem Building Blocks
sales at asischem.com 
p.+1 866 609 8657
f.+1 617 837 2114
21188
2014-04-29
23925 download
676
60
NYA
90%:7934
80%:3200
70%:1378
60%:610
Capot Chemical
sales at capotchem.com 
p.+86 571 855 867 18
f.+86 571 858 647 95
21535
2012-08-28
19707 download
906
720
NYA
90%:11426
80%:5119
70%:2253
60%:1105
Toslab
toslab at toslab.com 
p.+7 343 3754135
f.+7 343 3754135
22065
2011-12-07
29502 download
4935
6315
NYA
90%:8345
80%:4584
70%:2779
60%:1622
ZereneX
enquiries at zerenex-molecular.com 
p.+44 1204 527700
f.no fax
23218
2012-05-09
30382 download
7
4
NYA
90%:14963
80%:7996
70%:3469
60%:1108
BioSynth
welcome at biosynth.ch 
p.+41 71 858 20 20
f.+41 71 858 20 30
24163
2015-11-30
23034 download
1019
3176
NYA
90%:12202
80%:6694
70%:3302
60%:1568
Innovapharm Building Blocks
reag at nbi.com.ua 
p.+38 044 5599572
f.+38 044 4927309
24673
2014-05-06
30824 download
555
331
NYA
90%:13422
80%:7121
70%:3387
60%:1467
Angene Building Blocks
contact at an-gene.com 
p.no phone
f.no fax
24717
2014-06-17
22840 download
1098
128
NYA
90%:13162
80%:5372
70%:2219
60%:1000
AnalytiCon Discovery Natural Derivatives
sales at ac-discovery.com 
p.+49 331 2300-335
f.+49 331 2300-333
24800
2013-02-17
25898 download
6
3748
NYA
90%:5868
80%:1280
70%:347
60%:115
ChemDiv BuildingBlocks
chemdiv at chemdiv.com 
p.858-794-4860
f.858-794-4931
25952
2015-01-13
30385 download
393
935
NYA
90%:15583
80%:8618
70%:4170
60%:1759
Aronis
aronis at aronis.ru 
p.+79265780336
f.+7 495 4265336
26677
2013-02-14
31091 download
831
119
NYA
90%:11397
80%:3681
70%:1423
60%:614
Toronto Research Chemicals
info at trc-canada.com 
p.+1 416 665 9696
f.+1 416 665 4439
26908
2013-07-15
26234 download
409
10828
NYA
90%:12502
80%:7755
70%:4265
60%:2100
Alinda Building Blocks
alinda at alinda.ru 
p.+7 (495) 989-96-71
f.+7 (495) 989-96-72
27417
2015-04-15
32445 download
365
169
NYA
90%:16138
80%:8338
70%:3826
60%:1519
FineTech
sales at finetechnology-ind.com 
p.phone
f.fax
30097
2013-03-13
26626 download
3204
2697
NYA
90%:14367
80%:7450
70%:3571
60%:1728
Florida Heterocyclic Compounds
compounds at chem.ufl.edu 
p.do not call
f.+1 352 392 9199
32056
2013-03-12
41192 download
3467
2696
NYA
90%:17975
80%:10450
70%:5308
60%:2417
Wisdom Chemicals
xd_cao at wisdompharma.com 
p. +86-513-82227901
f.+86-513-82227902
32420
2012-10-01
32698 download
0
32662
NYA
90%:11360
80%:2054
70%:347
60%:128
Apexmol Building Blocks
sales at apexmol.com 
p.+86 108 290 0393
f.+86 108 246 3736
33484
2015-06-21
35635 download
502
2715
NYA
90%:14393
80%:6015
70%:2582
60%:1227
PKChem
mail at pkchem.ru 
p.no phone
f.no fax
34021
2013-04-22
29565 download
2481
293
NYA
90%:3296
80%:979
70%:409
60%:178
Vitas-M BB
irina at vitasmlab.com 
p.+31 (0) 55 50 500 33
f.+31 (0) 55 50 500 34
34132
2015-12-02
40321 download
741
0
NYA
90%:18673
80%:9258
70%:4273
60%:1816
Zylexa Pharma
sales at zylexa-pharma.com 
p.+44 (0) 1204 841765
f.no fax
34154
2012-05-07
39162 download
1114
1782
NYA
90%:10747
80%:3373
70%:1043
60%:409
Alfa-Aesar
info at alfa.com 
p.+1 978 521 6300
f.+1 978 521 6350
34687
2015-08-03
34300 download
2954
3901
NYA
90%:14723
80%:5930
70%:2412
60%:1040
Apollo Scientific
sales at apolloscientific.co.uk 
p.+44 161 406 0505
f.+44 161 406 0506
42187
2012-09-13
43287 download
3291
1657
NYA
90%:23944
80%:11328
70%:5093
60%:2199
ZereneX Building Blocks
enquiries at zerenex-molecular.com 
p.+44 1204 527700
f.no fax
47943
2012-05-11
49944 download
1124
7536
NYA
90%:13519
80%:5889
70%:2854
60%:1348
Bide Pharmatech BB
sales at bidepharmatech.com 
p. +86-21-61629020
f.+86 21 61629029
48565
2015-02-02
44654 download
1879
19
NYA
90%:23729
80%:9134
70%:3842
60%:1698
Maybridge
Maybridge.Sales at thermofisher.com 
p.+44 1840 772046
f.+44 1840 772208
54298
2015-04-21
70150 download
1544
5258
NYA
90%:38698
80%:22892
70%:11019
60%:4163
Synthon-Lab
sl at synthon-lab.com 
p.+7 812 428 4885
f.+7 812 428 4885
54436
2011-10-07
81096 download
2645
2209
NYA
90%:18466
80%:6009
70%:2260
60%:882
Alfa Chemistry
sales at alfa-chemistry.com 
p.no phone
f.no fax
56389
2015-08-03
46863 download
7956
8287
NYA
90%:29234
80%:17760
70%:8204
60%:3577
IBScreen NP
screen at ibscreen.com 
p.+7 (095) 788 0651
f.+7 (095) 788 0652
56799
2015-06-21
84215 download
6199
7030
NYA
90%:15298
80%:6892
70%:3279
60%:1469
BePharm Building Blocks
sales at bepharm.com 
p.+86-518-16456
f.+86-21-51816457
57018
2013-04-01
52499 download
2096
312
NYA
90%:28114
80%:10397
70%:4227
60%:1852
Combi-Blocks
sales at combi-blocks.com 
p.+1 877 525 6257
f.+1 858 635 8991
58549
2013-11-29
53043 download
1383
13245
NYA
90%:24768
80%:8617
70%:3414
60%:1471
Synblock
sales at synblock.com 
p.+1 514 572 9596
f.nofax
61600
2014-01-27
55974 download
939
28078
NYA
90%:25731
80%:8738
70%:3356
60%:1470
Anward
sales at anward.com 
p.+852 8191 6999
f.+852 2723 7175
62108
2013-02-19
56203 download
3067
1665
NYA
90%:28857
80%:10424
70%:4087
60%:1776
PBMR Labs Building Blocks
info at pbmr.com.ua 
p.+38 044 5599081
f.+38 044 3614520
62771
2013-02-16
72165 download
654
16729
NYA
90%:23126
80%:10826
70%:5059
60%:2157
Matrix Scientific
sales at matrixscientific.com 
p.800-580-6330
f.803-788-9419
65271
2012-09-17
74333 download
1419
707
NYA
90%:33502
80%:13420
70%:5203
60%:1943
BOC Sciences BB
sales at bocsci.com 
p.+1 631 504 6093
f.+1 631 614 7828
67816
2014-05-27
64204 download
8564
17008
NYA
90%:38844
80%:23975
70%:11398
60%:5079
SynQuest Building Blocks
info at synquestlabs.com 
p.+1 877 435 8676
f.+1 386 462 7097
72440
2015-07-24
69145 download
7381
4945
NYA
90%:37130
80%:15709
70%:6601
60%:2730
Zylexa Pharma BB
sales at zylexa-pharma.com 
p.+44 (0) 1204 841765
f.no fax
73058
2012-05-07
70265 download
1478
15843
NYA
90%:28953
80%:11564
70%:4588
60%:1871
Chemstep
info at chemstep.com 
p.+33 556 405 186
f.+33 524 842 817
73375
2014-02-14
87546 download
1182
56972
NYA
90%:45206
80%:25208
70%:12225
60%:5428
Oakwood Chemical
sales at oakwoodchemical.com 
p.+1 803 739 8800
f.+1 803 739 6957
73751
2013-08-26
76767 download
2077
249
NYA
90%:32577
80%:12121
70%:4536
60%:1811
3B Scientific Corporation
sales at 3bsc.com 
p.847 281 9822
f.847 281 9855
75732
2014-08-08
74528 download
7913
3844
NYA
90%:35123
80%:16117
70%:7087
60%:3036
Debye Scientific Building Blocks
sales at debyesci.com 
p.00 852 21376140
f.00 852 31149072
77710
2015-04-15
73208 download
2964
5762
NYA
90%:40391
80%:16625
70%:6406
60%:2520
KeyOrganics
enquiries at keyorganics.ltd.uk 
p.+44 1840 212137
f.+44 1840 213712
78171
2015-08-03
94554 download
1294
4947
NYA
90%:46106
80%:22385
70%:9530
60%:3379
Tetrahedron Building Blocks
sales at thsci.com 
p.+86 (0) 571 8848 9473
f.+86 (0)571 8848 9473
90917
2014-01-29
84208 download
8534
6466
NYA
90%:40162
80%:16935
70%:6989
60%:3008
TimTec Building Blocks
info at timtec.com 
p.(302) 292-8500
f.(302) 292-8520
43299
2013-01-15
108678 download
1108
1518
NYA
90%:46304
80%:18249
70%:7053
60%:2694
The following limits are in effect:
  • Molecules per mol2 or SDF format file: 100,000
  • Entries per flexibase file 20,000
  • Typical size of mol2/sdf/flexibase files: 20 to 100 MB
  • Number of large files that may be downloaded concurrently: 2
In the downloads above, we offer four formats: SMILES, mol2, SDF, and flexibase formats. Most docking programs we know of use mol2. We urge you to not download Flexibaseunless you are using DOCK3.5.54.

We have generated protonated forms in 3 pH ranges. The reference structure ("ref") is a single representative structure at pH 7. The middle pH range ("mid") contains additional protonated forms obtained by titrating protons with pKa between 5.75 and 8.25. The low pH range ("lo") contains additional protonated forms between pH 4.5-7 and the high pH range ("hi") contains additional protonation forms between pH 7-9.5.

Databases are divided into chunks for easier download. mol2 and sdf slices are 100MB or less uncompressed. Flexibase are 160MB or less uncompressed.

To download all files in the usual pH range (5.75-8.25) use "Usual". To download databases for metalloenzymes use "Metal", which adds the pH range 7-9.5 to usual above. For the entire pH range 4.5-9.5 please use "All".

We also offer tables of Molecular Properties, purchasing information, and Inchi files.

A product of BCIRC, the Bioinfomatics and Chemical Informatics Research Center @ UCSF. Last updated Aug 6, 2009. questions and discussion to zinc-fans at docking.org; bug reports to support at docking.org; any other correspondence to comments at docking.org. Terms of use. Privacy policy.